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Heterobiaryl synthesis by contractive C–C coupling via P(V) intermediates: M.C. Hilton, X. Zhang, B.T. Boyle, J.V. Alegre-Requena, R.S. Paton, A. McNally, Science, 2018, 362, 799. Featured in: C&EN, Chemistry World,, and Synfacts.

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A Unified Approach to Couple Aromatic Heteronucleophiles to Azines and Pharmaceuticals:  R.G. Anderson, B.M. Jett, A. McNally, Angew. Chem. Int. Ed. 2018, 57, 12514. Featured in OPRD Research Highlights: doi:10.1021/acs.oprd.8b00283 and Synfacts: doi:10.1055/s-0037-1610975

aromatic heteronucleophiles.PNG

Site-Selective Switching Strategies to Functionalize Polyazines:  R.D. Dolewski, P.J. Fricke, A. McNally, J. Am. Chem. Soc. 2018140, 8020.


A Strategy to Aminate Pyridines, Diazines, and Pharmaceuticals via Heterocyclic Phosphonium Salts: C. Patel, M. Mohnike, M.C. Hilton, A. McNally, Org. Lett., 2018, 20, 2607.


A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines and Pharmaceuticals: J. L. Koniarczyk, D. Hesk, A. Overgard, I. W. Davies, and A. McNally, J. Am. Chem. Soc. 2018140, 1990.  Featured in Nature Reviews Chemistry: doi:10.1038/s41570-018-0119

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Synthesis of Biotinylated Diazinon: Lessons Learned for Biotinylation of Thiophosphate Esters: K.G. Nottingham, A. McNally, B.R. McNaughton, Tetrahedron Lett. 201859, 234-237.


Selective Formation of Heteroaryl Thioethers via a Phosphonium Ion Coupling Reaction: R.G. Anderson, B.M. Jett, A. McNally, Tetrahedron201874, 3129-3136.


4-Selective Pyridine Functionalization Reactions via Heterocyclic Phosphonium Salts: R.D. Dolewski, M.C. Hilton, A. McNally, Synlett201829, 8-14.


Phosphonium Salts as Pseudohalides: Regioselective Nickel-Catalyzed Cross-Coupling of Complex Pyridines and Diazines: X. Zhang, A. McNally, Angew. Chem. Int. Ed. 201756, 9833-9836.  Featured in OPRD Research Highlights:  doi:10.1021/acs.oprd.7b00286 


Selective Functionalization of Pyridines via Heterocyclic Phosphonium Salts: M.C. Hilton, R.D. Dolewski, A. McNally, J. Am. Chem. Soc. 2016, 138, 13806-13809.  Featured in Chemistry World.


Stereoselective Synthesis: Molecular Editing of Carbohydrates: A. McNally, Nature Chem. 2015, 7, 539-541.


Publications prior to CSU


Palladium-Catalyzed C–H Activation of Aliphatic Amines to Give Strained Nitrogen Heterocycles: A. McNally, B. Haffemeyer, B. S. L. Collins, M. J. Gaunt. Nature 2014, 510, 129-133.

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Organocatalytic C–H Bond Arylation of Aldehydes to Bis-Heteroaryl Ketones: Q-Y. Toh, A. McNally, S. Vera, N. Erdmann, M.J. Gaunt, J. Am. Chem. Soc. 2013, 135, 3772- 3775.

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Discovery of an α-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity: A. McNally, C.K. Prier, D.W.C. MacMillan, Science 2011, 334, 1114-1117.

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Enantioselective Organocatalysis: M.J. Gaunt, C.C.C Johansson; A. McNally, N.T. Vo, Drug Discov. Today 2007, 2, 8-27.


Organocatalytic Sigmatropic Reactions: Development of a [2,3]-Wittig Rearrangement via Secondary Amine Catalysis: A. McNally, B. Evans, M.J. Gaunt, Angew. Chem. Int. Ed. 2006, 45, 2116-2119.

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